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Carlos Alberto Manssour Fraga

• Campos, HC; Rocha, MD; Viegas, FPD; Bicastro, PC; Fossaluzza, PC; Fraga, CAM; Barreiro, EJ; Viegas Júnior, C. The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders I: Parkinson’s disease. CNS & Neurological Disorders. Drug Targets, 10, 239-250, 2011.

• Rocha, MD; Silva, FM; Viegas, FPD; Campos, HC; Nicastro, PC; Fossaluzza, PC; Fraga, CAM; Barreiro, EJ; Viegas Júnior, C. The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders II: Alzheimer’s disease. CNS & Neurological Disorders. Drug Targets, 10, 251-270, 2011.

• Fraga, AGM; Silva, LL; Fraga, CaAM; Barreiro, EJ. CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. European Journal of Medicinal Chemistry, 46, 349-355, 2011.

• Avila, CM; Lopes, AB; Silva, LL; Romeiro, NC; Miranda, ALP; Sant'anna, CMR; Barreiro, EJ; Fraga, CAM. Structure-based design and biological profile of (e)-n-(4-nitrobenzylidene)-2-naphthohydrazide, a novel small molecule inhibitor of iκb kinase-β. European Journal of Medicinal Chemistry, 46, 1245-1253, 2011.

• Romeiro, LAS; Ferreira, MS; Silva LL; Castro, HC; Miranda, ALP; Silva, CLM; Noel, FG; Nascimento, JB; Araujo, CV; Tibiriçá, E; Barreiro, EJ; Fraga, CAM. Discovery of LASSBio-772, a 1,3-benzodioxole N-phenylpiperazine derivative with potent alpha 1A/D-Adrenergic receptor blocking properties. European Journal of Medicinal Chemistry, 46, 3000-3012, 2011.

• Braga, RC; Tôrres, ACB; Persiano, CB; Alves, RO; Fraga, Carlos AM; Barreiro, Eliezer J; Oliveira, Valéria de. Determination of the cardioactive prototype LASSBio-294 and its metabolites in dog plasma by LC-MS/MS: Application for a pharmacokinetic study. Journal of Pharmaceutical and Biomedical Analysis (Print), 55, 1024-1030, 2011.

• Barreiro, EJ; Kummerle, AE; Fraga, CAM. The methylation effect in medicinal Chemistry. Chemical Reviews, 111, 5215-5246, 2011.

• Oliveira, AA; Matos, CAS; Rennó, MN; Bertuzzi, MD; Ramalho, TC; Fraga, CAM; Franca, TCC. Molecular modeling studies of Yersinia pestis dihydrofolate reductase. Journal of Biomolecular Structure & Dynamics, 29, 351-367, 2011.

• Nascimento-Jr, NM; Kummerle, AE; Barreiro, EJ; Fraga, CAM. MAOS and Medicinal Chemistry: Some important examples from the last years. Molecules (Basel. Online), 16, 9274-9297, 2011.

• Barreiro, EJ; Lima, LM; Fraga, CAM. A arte de criar o artificial. Ciência Hoje, 48, 36-37, 2011.

Cláudia Lucia Martins da Silva

• Oliveira, SDS; Silva, CLM. Schistosomiasis differentially affects vasoconstrictor responses: up-regulation of 5-HT receptor-mediated aorta contraction. Memórias do Instituto Oswaldo Cruz (Impresso), 106, 456-460, 2011.

• Noël, F; Pimenta, PHC; Santos, AR; Tomaz, ECL; Quintas, LEM; CR; Silva, CLM; Férézou, JP. 2,3-Ivermectin ethyl secoester, a conjugated ivermectin derivative with leishmanicidal activity but without inhibitory effect on mammalian P-type ATPases. Naunyn-Schmiedeberg's Archives of Pharmacology, 383, 101-107, 2011.

• Oliveira, SDS; Quintas, LEM; Amaral, LS; Noël, F; Farsky, SH; Silva, CLM. Increased endothelial cell-leukocyte interaction in murine schistosomiasis: possible priming of endothelial cells by the disease. Plos One, 6, e23547, 2011.

• Romeiro, LAS; Silva, FM; Silva, LL; Castro, HC; Miranda, ALP; Silva, CLM; Noël, F; Nascimento, JB; Araújo, CV; Tibiriçá, E; Barreiro, EJ; Fraga, CAM. Discovery of LASSBio-772, a 1,3-benzodioxole N-phenylpiperazine derivative with potent alpha 1A/D-adrenergic receptor blocking properties. European Journal of Medicinal Chemistry, 46, 3000-3012, 2011.

Eliezer Jesus de Lacerda Barreiro

• Ribeiro, JCML; Fechine, FV; Ribeiro, MZML; Barreiro, EJ; Lima, LM; Ricardo, NMPS; Moraes, MEA; Moraes, MO. Potential inhibitory effect of LASSBio-596, a new thalidomide hybrid, on inflammatory corneal angiogenesis in rabbits. Ophthalmic Research, 48, 177-185, 2012.

• Fraga, AGM; Silva, LL; Fraga, CAM; Barreiro, EJ. CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. European Journal of Medicinal Chemistry, 46, 349-355, 2011.

• Campos, CC; Rocha, MD; Viegas, FPD; Nicastro, PC; Fossaluzza, PC; Fraga, CA M; Barreiro, EJ; Viegas JR, C. The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders I: Parkinson’s Disease. Current Drug Targets. CNS & Neurological Disorders, 10, 239-250, 2011.

• Avila, CM; Lopes, AB; Gonçalves, AS; Silva, LL; Romeiro, NC; Miranda, ALP; Sant’Anna, CMR; Barreiro, EJ;Fraga, CAM. Structure-based design and biological profile of (E)-N-(4-Nitrobenzylidene)-2-naphthohydrazide, a novel small molecule inhibitor of IkB kinase-? European Journal of Medicinal Chemistry, 1245-1253, 2011.

• Romeiro, LAS; Ferreira, MS; Silva, LL; Castro, HC; Miranda, ALP; Silva, CLM; Noel, F; Nascimento, JB; Araujo, CV; Tibiriça, E; Barreiro, EJ ; Fraga, CAM . Discovery of LASSBio-772, a 1,3-benzodioxole n-phenylpiperazine derivative with potent alpha 1a/d-adrenergic receptor blocking properties. European Journal of Medicinal Chemistry, 3000-3012, 2011.

• Barreiro, EJ Kummerle, AE; Fraga, CAM. The methylation effect in medicinal chemistry. Chemical Reviews, 111, 5215-5246, 2011.

• Parrilha, GL; Vieira, RP; Rebolledo, AP; Mendes, IC; Lima, LM; Barreiro, EJ; Piro, OE; Castellano, EE; Beraldo, H. Binuclear zinc(II) complexes with the anti-inflammatory compounds salicylaldehyde semicarbazone and salicylaldehyde-4-chlorobenzoyl hydrazone (H2LASSBio-1064). Polyhedron, 30, 1891-1898, 2011.

• Júnior, WB; Alexandre-Moreira, MS; Alves, MA; Perez-Rebolledo, A; Parrilha, GL; Castellano, EE; Piro, OE; Barreiro, EJ; Lima, LM; Beraldo, H. Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (H2LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H2LASSBio-1064) and their zinc(ii) complexes. Molecules (Basel. Online), 16, 6902-6915, 2011.

• Casquilho, NV; Carvalho, GMC; Alves, JLCR; Machado, MN; Soares, RM; Azevedo, SMFO; Lima, LM; Barreiro, EJ;Valença, SS; Carvalho, AR; Faffe, DS; Zin, WA. LASSBio-596 per os avoids pulmonary and hepatic inflammation induced by microcystin-LR. Toxicon (Oxford), 58, 195-201, 2011.

• Nascimento-Júnior, NM; Kümmerle, AE; Barreiro, EJ; Fraga, CAM. MAOS and medicinal chemistry: some important examples from the last years. Molecules (Basel. Online), 16, 9274-9297, 2011.

• Lima, AB; Machado, AL; Simon, P; Cavalcante, MM; Rezende, DC; Silva, GMS; Silva, GM; Nascimento, PG; Quintas, LEM; Cunha, FQ; Arreiro, EJ; L, ML; Koatz, VLG. Anti-inflammatory effects of LASSBio-998, a new drug candidate designed to be a p38 MAPK inhibitor, in an experimental model of lung inflammation. Pharmacological Reports, 63, 1029-1039, 2011.

• Braga, RC; Fraga, CAM; Andrade, CH; Oliveira, V; Alves, VM; Barreiro, EJ. Combination of docking, molecular dynamics and quantum mechanical calculations for metabolism prediction of 3,4-methylenedioxybenzoyl-2-thienylhydrazone. Journal of Molecular Modeling (Print), 18, 1-29, 2011.

• Braga, RC; Barreiro, EJ; Fraga, CAM; Tãrres, ACB; Alves, RO; Oliveira, V; Persiano, CB. Determination of the cardioactive prototype LASSBio-294 and its metabolites in dog plasma by LCa MS/MS: Application for a pharmacokinetic study. Journal of Pharmaceutical and Biomedical Analysis (Print), 55, 1024-1030, 2011.

• Barbosa MLC; Fumian, M; Miranda, ALP; Barreiro, EJ. Therapeutic approaches for tumor necrosis factor inhibition. Brazilian Journal of Pharmaceutical Sciences (Impresso), 47, 427, 2011.

Floriano Paes Silva Junior

• Teixeira, SS; Silveira, LB; Silva, FMN; Marchi-Salvador, DP; Silva, FP; Izidoro, LFM; Fuly, AL; Juliano, MA; Santos, CR; Murakami, MT; Sampaio, SV; Silva, SL; Soares, AM. Molecular characterization of an acidic phospholipase A2 from Bothrops pirajai snake venom: synthetic C-terminal peptide identifies its antiplatelet region. Archives of Toxicology, 85, 1219-1233, 2011.

François Germain Noel

• Noel, F; Pimenta, PHC; Santos, AR; Tomaz, ECL; Quintas, LuEM; Kaiser, CR; Silva, CLM; Férézou, JP. 2,3-Ivermectin ethyl secoester, a conjugated ivermectin derivative with leishmanicidal activity but without inhibitory effect on mammalian P-type ATPases. Naunyn-Schmiedeberg's Archives of Pharmacology, 383, 101-107, 2011.

• Touza, NA; Pôças, ESC; Quintas, LEM; Cunha-Filho, G; Santos, ML; Noël, F. Inhibitory effect of combinations of digoxin and endogenous cardiotonic steroids on Na+/K+-ATPase activity in human kidney membrane preparation. Life Sciences (1973), 88, 39-42, 2011.

• Romeiro, LAS; Ferreira, MS; Silva, LL; Castro, HC; Miranda, ALP; Silva, CLM; Noel, F; Nascimento, JB; Araujo, CV; Tibiriça, E; Barreiro, EJ; Fraga, CAM . Discovery of LASSBio-772, a 1,3-Benzodioxole N-Phenylpiperazine Derivative with Potent Alpha 1A/D-Adrenergic Receptor Blocking Properties. European Journal of Medicinal Chemistry, 46, 3000-3012, 2011.

• Bettero, G; Salles, L; Figueira, RR; Poser, G; Rates, S; Noël, F; Quintas, LEM. Effect of valepotriates isolated from on rat P-type ATPases. Planta Medica, 77, 1702-1706, 2011.

• Oliveira, SDS; Quintas, LEM; Amaral, LS; Noël, F; Farsky, SH; Silva, CLM. Increased endothelial cell-leukocyte interaction in murine schistosomiasis: possible priming of endothelial cells by the disease. Plos One, 6, e23547, 2011.

Gisele Zapata Sudo

• Abriel, D; Pontes, LB; Silva, JS; Sudo, RT; Garden, SJ; Corrêa, MB; Pinto, AC; Zapata-Sudo, G . Pharmacological activity of novel 2-hydroxyacetophenone isatin derivatives on cardiac and vascular smooth muscle in rats. Journal of Cardiovascular Pharmacology, 57, 20-27, 2011.

• Landgraf, SS; Wengert, M; Silva, JS; Zapata-Sudo, G; Sudo, RT; Takiya, CM; Pinheiro, AA; Caruso-Neves, C. Changes in angiotensin receptors expression play a pivotal role in the renal damage observed in spontaneous hypertensive rats. American Journal of Physiology. Renal Physiology, 300, F499-F510, 2011.

• Kiuchi, MG; Zapata-Sudo, G; Trachez, MM; Ririe, D; Sudo, RT. Influence of age on bupivacaine cardiotoxicity. Anesthesia and Analgesia, 112, 574-580, 2011.

• Medei, E; Raimundo, JM; Nascimento, JHM; Sudo, RT; Zapata-Sudo, G. Inhibition of L-type calcium current by tramadol and enantiomers in cardiac myocytes from rats. Arquivos Brasileiros de Cardiologia (Impresso), 97, 324-330, 2011.

Lidia Moreira Lima

• Santos, JL; Bosquesi, PL; Varanda, EA; Lima, LM; Chung, MC. Assessment of the in vivo genotoxicity of new lead compounds to treat sickle cell disease. Molecules (Basel. Online), 16, 2982-2989, 2011.

• Casquilho, NV; Carvalho, GMC; Alves, JLCR; Machado, MN; Soares, RM; Azevedo, SMFO; Lima, LM; Barreiro, EJ; Valença, SS; Carvalho, AR; Faffe, DS; Zin, WA. LASSBio-596 per os avoids pulmonary and hepatic inflammation induced by microcystin-LR. Toxicon (Oxford), 58, 195-201, 2011.

• Lima, LM; Lanaro, C; Gambero, SH; Franco-Penteado, CF; Alexandre-Moreira, MS; Wade, M; Yerigenahally, S; Kutlar, A; Meiler, SE; Costa, FF; Chung, M. Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms. Journal of Medicinal Chemistry, 54, 5811-5819, 2011.

• Lima, ACB; Machado, AL; Simon, P; Cavalcante, MM; Silva, GMS; Nascimento, PGBD; Quintas, LEM; Cunha, FQ; Barreiro, EJ; Lima, LM; Koatz, VLG. Anti-inflammatory effects of LASSBio-998, a new drug candidate designed to be a p38 MAPK inhibitor, in an experimental model of acute lung inflammation. Pharmacological Reports, 63, 1029-1039, 2011.

• Barbosa, MLC; Fumian, MM; Miranda, ALP; Barreiro, EJ; Lima, LM. Therapeutic approaches for tumor necrosis factor inhibition. Brazilian Journal of Pharmaceutical Sciences. Brazilian Journal of Pharmaceutical Sciences (Impresso), 47, 427-446, 2011.

• Barreiro, EJ; Lima, LM; Fraga, CAM. A arte de criar o artificial. Ciência Hoje, 48, 36-37, 2011.

• Bispo, W; Lima, LM; Barreiro, EJ; Alves, MA; Alexandre-Moreira, MS; Beraldo, H; Castellano, EE; Parrilha, GL; Perez-Rebolledo, A; Piro, OE. Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (h2LASSBIO-466), salicylaldehyde 4-chlorobenzoyl hydrazone (h2LASSBIO-1064) and their zinc(ii) complexes. Molecules (Basel. Online), 16, 6902-6915, 2011.

• Parrilha, GL; Castellano, EE; Barreiro, EJ; Mendes, IC; Rebolledo, AP; Lima, LM; Piro, OE; Vieira, RP; Beraldo, H. Binuclear zinc(II) complexes with the anti-inflammatory compounds salicylaldehyde semicarbazone and salicylaldehyde-4-chlorobenzoyl hydrazone (H2LASSBio-1064). Polyhedron, 30, 1891-1898, 2011.

• Pontes, LB; Antunes, F; Sudo, RT; Raimundo, JM; Lima, LM; Barreiro, EJ; Zapata-Sudo, G. Vasodilatory activity and antihypertensive profile mediated by inhibition of phosphodiesterase type 1 induced by a novel sulfonamide compound. Fundamental & Clinical Pharmacology, 00, p. no-no, 2011.

Lucienne da Silva Lara Morcillo

• Vieira-Filho, LD; Lara, LS; Silva, PA; Santos, FTJ; Luzardo, R; Oliveira, FST; Paixão, ADO; Vieyra, A. Placental malnutrition changes the regulatory network of renal Na-ATPase in adult rat progeny: Reprogramming by maternal α-tocopherol during lactation. Archives of Biochemistry and Biophysics (Print), 505, 91-97, 2011.

• Gonzalez, AA; Lara, LS; Luffman, C; Seth, DM; Prieto, MC. Soluble form of the (pro)renin receptor is augmented in the collecting duct and urine of chronic angiotensin ii-dependent hypertensive rats. Hypertension, 57, 859-864, 2011.

• Gonzalez, AA; Liu, L; Lara, LS; Seth, DM; Navar, LG; Prieto, MC. Angiotensin II stimulates renin in inner medullary collecting duct cells via protein kinase c and independent of epithelial sodium channel and mineralocorticoid receptor activity. Hypertension, 57, 594-599, 2011.

• Luzardo, R; Silva, PA; Einicker-Lamas, M; Ortiz-Costa, S; Carmo, MGT; Vieira-Filho, LD; Paixão, ADO; Lara, LS; Vieyra, A. Metabolic programming during lactation stimulates renal na+ transport in the adult offspring due to an early impact on local angiotensin ii pathways. Plos One, 6, e21232, 2011.

• Lara, LS; McCormack, M; Semprum-Prieto, LC; Shenouda, S; Majid, DSA; Kobori, H; Navar, LG; Prieto, MC. AT1 receptor-mediated augmentation of angiotensinogen, oxidative stress, and inflammation in ANG II-salt hypertension. American Journal of Physiology. Renal Physiology, 302, F85-F94, 2011.

• Prieto, MC; Gonzalez-Villalobos, RA; Botros, FT; Martin, VL; Pagan, J; Sato, R; Lara, LS; Feng, Y; Fernandez, F; Kobori, H; Casarini, DE; Navar, LG. Reciprocal changes in renal ACE/Ang II and ACE2/Ang 1-7 are associated with enhanced collecting duct renin in Goldblatt hypertensive rats. American Journal of Physiology. Renal, Fluid and Electrolyte Physiology (Cessou em 1996. Cont. ISSN 1931-857X American Journal of Physiology. Renal Ph, 300, F749-F755, 2011.

Luis Eduardo Menezes Quintas

• Noël, F; Pimenta, PHC; Santos, AR; Tomaz, ECL; Quintas, LEM; Kaiser, CR; Silva, CLM; Férézou, JP. 2,3-Ivermectin ethyl secoester, a conjugated ivermectin derivative with leishmanicidal activity but without inhibitory effect on mammalian P-type ATPases. Naunyn-Schmiedeberg's Archives of Pharmacology, 383, 101-107, 2011.

• Touza, NA; Pôças, ESC; Quintas, LEM; Cunha-Filho, G; Santos, ML; Noël, F. Inhibitory effect of combinations of digoxin and endogenous cardiotonic steroids on Na⁺/K⁺-ATPase activity in human kidney membrane preparation. Life Sciences (1973), 88, 39-42, 2011.

• Lima, AB; Legora-Machado, A; Simon, PL; Cavalcante, MC ; Rezende, DC; Silva, GMS; Nascimento, PG; Quintas, LEM Corresponding Author; Cunha, F;Barreiro, EJ; LIma, LM; Koatz, VLG . Anti-inflammatory effect of LASSBio-998, a new drug candidate designed as p38 MAPK inhibitor, in an experimental model of acute lung inflammation. Pharmacological Reports, 63, 1029-1039, 2011.

• Oliveira, SDS; Quintas, LEM; Amaral, LS; Noël, F; Farsky, SH; Silva, CLM. Increased endothelial cell-leukocyte interaction in murine schistosomiasis: possible priming of endothelial cells by the disease. Plos One, 6, e23547, 2011.

• Bettero, G; Salles, L; Figueira, RR; Poser, G; Rates, S; Noël, F; Quintas, LEM. Effect of valepotriates isolated from on rat P-type ATPases. Planta Medica, 77, 1702-1706, 2011.

• Quintas, LEM; S. Gram, KR; Silveira, ER; Lopes, DVS; Pôças, ESC . Pharmacokinetic modifications and drug-drug interactions in clinical monitoring of the elderly: a short review. Pharmaceutica Analytica Acta, 02, 2-9, 2011.

Marco Aurélio Martins

• Olsen, PC; Ferreira, TPT; Serra, MF; Farias-Filho, FA; Fonseca, BP; Viola, JPB; Cordeiro, RSB; Silva, PMR; Costa, JCS; Martins, MA. Lidocaine-derivative JMF2-1 prevents ovalbumin-induced airway inflammation by regulating the function and survival of T cells. Clinical and Experimental Allergy (Print), 41, 250-259, 2011.

• Saraiva, SA; Silva, AL; Xisto, DG; Abreu, SC; Silva, JD; Silva, PL; Teixeira, TPF; Parra, ER; Carvalho, ALN; Annoni, R; Mauad, T; Capelozzi, VL; Silva, PMR; Martins, MA; Rocco, PRM. Impact of obesity on airway and lung parenchyma remodeling in experimental chronic allergic asthma. Respiratory Physiology & Neurobiology, 177, 141-148, 2011.

• Carvalho, VF; Florim, LT; Barreto, EO; Torres, RC; Batista, MM; Amendoeira, FC; Cordeiro, RSB; Martins, MA; Silva, PMR. Inhibition of advanced glycation end products by aminoguanidine restores mast cell numbers and reactivity in alloxan-diabetic rats. European Journal of Pharmacology, 669, 143-148, 2011.

Marília Zaluar Passos Guimarães

• Marques-da-Silva, C; Chaves, MM; Castro, NG; Coutinho-Silva, R; Guimaraes, MZP. Colchicine inhibits cationic dye uptake induced by ATP in P2X2- and P2X7 receptor-expressing cells: implications for its therapeutic action. British Journal of Pharmacology, 163, 912-926, 2011.

Newton Gonçalves de Castro

• Marques-da-Silva, C; Chaves, MM; Castro, NG; Coutinho-Silva, R; Guimaraes, MZP. Colchicine inhibits cationic dye uptake induced by ATP in P2X2- and P2X7 receptor-expressing cells: implication for its therapeutic action. British Journal of Pharmacology, 163, 912-926, 2011.

• Oliveira, DR; Costa, ALMA; Leitão, GG; Castro, NG; Santos, JP; Leitão, SG. Estudo etnofarmacognóstico da saracuramirá (Ampelozizyphus amazonicus Ducke), uma planta medicinal usada por comunidades quilombolas do Município de Oriximiná-PA, Brasil. Acta Amazonica (Impresso), 41, 383-392, 2011.

Nubia Boechat

• Boechat, N; Wardell, JL; Wardell, Solange MSV; Bastos, MM. Structures of two N-{2-([(5-amino-1,3,4-thiadiazol-2-yl)difluoromethyl]-4-halophenyl}acetamides. Journal of Chemical Crystallography, 41, 874-879, 2011.

• Magalhães, JL; Antunes, A; Boechat, N . Laboratórios farmacêuticos oficiais e sua relevância para saúde pública do Brasil. RECIIS. Revista eletrônica de comunicação, informação & inovação em saúde (Edição em português. Online), 5, 367, 2011.

• Boechat, N; Ferreira, VF; Ferreira, SB; Ferreira, MLG; Silva, FC; Bastos, MM; Costa, MS; Lourenço, MCS; Pinto, AC; Krettli, AU; Aguiar, AC; Teixeira, BM; Silva, NV; Martins, PRC; Bezerra, FAFM; Camilo, ALS; Silva, GP; Costa, CCP. Novel 1,2,3-triazole derivatives for use against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain. Journal of Medicinal Chemistry, 54, 5988-5999, 2011.

• Boechat, N; Pinheiro, LCS; Santos-Filho, OA; Silva, IC. Design and synthesis of new n-(5-trifluoromethyl)-1h-1,2,4-triazol-3-yl benzenesulfonamides as possible antimalarial prototypes. Molecules (Basel. Online), 16, 8083-8097, 2011.

• Boechat, N; Ferreira, MLG; Bastos, MM; Wardell, JL; Wardell, SMSV; Tiekink, ERT. [1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl]methanol hemihydrate. Acta Crystallographica. Section E, E-67, 2934-2935, 2011.

Patricia Dias Fernandes

• Marinho, DG; Alviano, DS; Matheus, ME; Alviano, CS; Fernandes, PD. The latex obtained from Hancornia speciosa Gomes possesses anti-inflammatory activity. Journal of Ethnopharmacology, 135, 530-537, 2011.

• Radulovic, NS; Miltojevic, AB; McDermott, M; Waldren, S; Parnell, JA; Pinheiro, MMG; Fernandes, PD; Menezes, FS. Identification of a new antinociceptive alkaloid isopropyl N-methylanthranilate from the essential oil of Choisya ternata Kunth. Journal of Ethnopharmacology, 610-619, 2011.

• Guilhon, CC; Raymundo, LJRP; Alviano, DS; Blank, AF; Arrigoni-Blank, MF; Matheus, ME; Cavalcanti, SCH; Alviano, CS; Fernandes, PD. Characterisation of the anti-inflammatory and antinociceptive activities and the mechanism of the action of Lippia gracilis essential oil. Journal of Ethnopharmacology, 135, 406-413, 2011.

• Souza, PAV; Palumbo, A; Alves, LM; Souza, VP; Cabral, LM; Fernandes, PD; Takiya, CM; Menezes, FS; Nasciutti, LE. Effects of a nanocomposite containing Orbignya speciosa lipophilic extract on Benign Prostatic Hyperplasia. Journal of Ethnopharmacology, 135, 135-146, 2011.

• Raymundo, LJRP; Guilhon, CC; Alviano, DS; Matheus, ME; Antoniolli, AR; Cavalcanti, SCH; Alves, PB; Alviano, CS; Fernandes, PD. Characterisation of the anti-inflammatory and antinociceptive activities of the Hyptis pectinata (L.) Poit essential oil. Journal of Ethnopharmacology, 134, 725-732, 2011.

• Fernandes, PD; Gomes, NM; Sirois, P. The bradykinin B1 receptor antagonist R-954 inhibits Ehrlich tumor growth in rodents. Peptides (New York, N.Y. 1980), 32, 1849-1854, 2011.

• Marinho, BG; Miranda, LSM; Meireles, BA; Vasconcellos, MLAA; Matheus, ME; Pereira, VLP; Fernandes, PD. Antinociceptive activity of (±)-(2S,6S)-(6-ethyl-tetrahydropyran-2-yl)-formic acid on acute pain in mice. Behavioural Pharmacology, 22, 564-572, 2011.

Patrícia Machado Rodrigues e Silva Martins

• Olsen, PC; Ferreira, TPT; Serra, MF; Farias-Filho, FA; Fonseca, BPF; Viola, J; Cordeiro, RSB; Silva, PMR; Costa, JC; MA, M. Lidocaine-derivative JMF2-1 prevents ovalbumin-induced airway inflammation by regulating the function and survival of T cells. Clinical and Experimental Allergy (Print), 41, 250-259, 2011.

• Queto, T; Vasconcelos, ZMF; Luz, LC ; Anselmo, C; Guine, AA; E Silva PMR; Farache, J; Cunha, JMT; Gaspar-Elsas, MI; Xavier-Elsas, P. G-CSF suppresses allergic pulmonary inflammation, downmodulating cytokine, chemokine and eosinophil production. Life Sciences (1973), 88, 830-838, 2011.

• Saraiva, SA; Silva, AL; Xisto DG; Abreu, S; Silva, PL; Ferreira, TPT; Parra-Cuentras, ER; Carvalho, ALN; Annoni, R; Capelozzi VL; Silva PMR; MA, Martins; Rocco, PR. Impact of obesity on airway and lung parenchyma remodeling in experimental chronic allergic asthma. Respiratory Physiology & Neurobiology, 177, 141-148, 2011.

• Meuserbatista, M; Correa, JM; Carvalho, VF; Soares, MJ; Farias-Filho, FA; Silva, PMR ; Lannes-Vieira, J; Silva, RC; Henrique-Pons, A. Mast cells function and death in Trypanosoma cruzi infection. The American Journal of Pathology (Print), x, xx-xxx, 2011.

• Carvalho, VF; Florim, L Torres; Barreto, EO; Torres, Rafael Carvalho; Meuserbatista, M; Amendoeira, FC; Cordeiro, RSB; Martins, MA, Silva, PMR. Inhibition of advanced glycation end products by aminoguanidine restores mast cell numbers and reactivity in alloxan-diabetic rats. European Journal of Pharmacology, 669, 143-148, 2011.

Paulo de Assis Melo

• Lopes, PFR; Lisboa, BCG; Frattini, F; Almeida, FM; Tomaz, MA; Matsumoto, PK; Langone, F; Lora, S; Melo, PA; Borojevic, R; Han, SW; Martinez, AMB. Enhancement of sciatic-nerve regeneration after VEGF gene therapy. Neuropathology and Applied Neurobiology (Print), 37, 600-612, 2011.

• Dip, EC; Pereira, NA; Melo, P A. Tongue angioedema: Antagonist response of anti-inflammatory drugs. Clinical Toxicology (Philadelphia, Pa. Print), 49, 153-160, 2011.

• Adade, CM; Cons, BL; Melo, P A; Souto-Padrón, T. Effect of Crotalus viridis viridis snake venom on the ultrastructure and intracellular survival of Trypanosoma cruzi. Parasitology (London. Print), 138, 46-58, 2011.

Paulo Roberto Ribeiro Costa

• Leão, RAC; Pinho, VD; Coelho, AS; Buarque, CD; Moraes, PF; Alonso, DA; Nájera, C; Costa, PRR. Microwave-promoted palladium-catalysed oxyarylation of dihydronaphthalene and chromenes by o-iodophenols and its acetates. European Journal of Organic Chemistry (Print), 2011, 3313-3316, 2011.

• Maia, RC; Vasconselos, FC; Bacelar, TS; Salustiano, EJ; Silva, LFR; Pereira, DL; Coelho, AM; Netto, CD; Silva, AJM; Rumjanek, VM; Costa, PRR. LQB-118, a pterocarpanquinone structurally related to lapachol [2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone]: a novel class of agent with high apoptotic effect in chronic myeloid leukemia cells. Investigational New Drugs, 29, 1143-1155, 2011.

• Cunha-Júnior, EF; Pacienza-Lima, W; Ribeiro, GA; Netto, CD; Canto-Cavalheiro, MM; Silva, AJM; Costa, PRR; Rossi-Bergman, B; Torres-Santos, EC. Effectiveness of the local or oral delivery of the novel naphthopterocarpanquinone LQB-118 against cutaneous leishmaniasis. Journal of Antimicrobial Chemotherapy (Print), 66, 1555-1559, 2011.

• Lima, EC; Souza, CC; Vaz, BG; Eberlin, MN; Dias, AG; Costa, PRR. DBU as a catalyst for the synthesis of amides via aminolysis of methyl esters. Journal of the Brazilian Chemical Society (Impresso), 22, 2186-2190, 2011.

• Leão, RAC; Moraes, PF; Pedro, MCBC; Costa, PRR. Synthesis of coumarins and neoflavones through zinc chloride catalyzed hydroarylation of acetylenic esters with phenols. Synthesis (Stuttgart), 2011, 3692-3696, 2011.

• Buarque, CD; Militão, GCG; Lima, DJB; Costa-Lotufo, LV; Pessoa, CO; Moraes, MO; Cunha-Júnior, EF; Torres-Santos, EC; Netto, CD; Costa, PRR. Pterocarpanquinones, aza-pterocarpanquinone and derivatives: synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis. Bioorganic & Medicinal Chemistry (Print), 19, 6885-6891, 2011.

• Castro, CP; Vasconselos, FC; Silva, AJM; Rumjanek, VM; Costa, PRR; Maia, RC. The new synthetic compound pterocarpanquinone lqb-118 induces apoptosis in acute myeloid leukemia cells through survivin and xiap downregulation. European Journal of Cancer, 47, S148-S148, 2011.

Roberto Takashi Sudo

• Kiuchi, MG; Zapata-Sudo, G; Trachez, MM; Ririe, D; Sudo, RT. Influence of Age on Bupivacaine Cardiotoxicity. Anesthesia and Analgesia, 112, 574-580, 2011.

• Costa, DG; Pontes, LB; Silva, JS; Sudo, RT; Correa, MB; Pinto, AC; Simon J; Zapata-Sudo, G. Pharmacological activity of novel 2-hydroxyacetophenone isatin derivatives on cardiac and vascular smooth muscle in rats. Journal of Cardiovascular Pharmacology, 57, 20-27, 2011.

• Landgraf, SS; Wengert, M; Silva JS ; Zapata-Sudo, G; Sudo, RT; Takiya, CM; Pinheiro, AAS; Caruso-Neves, C. Changes in angiotensin receptors expression play a pivotal role in the renal damage observed in spontaneous hypertensive rats. American Journal of Physiology. Renal Physiology, 300, F499-F510, 2011.

• Medei, E; Raimundo, JM; Nascimento, JHM; Trachez, MM; Sudo, RT; Zapata-Sudo, G. Inhibition of L-type calcium current by tramadol and enantiomers in cardiac myocytes from rats. Arquivos Brasileiros de Cardiologia (Impresso), 97, 324-331, 2011.

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